FAIS 2021 – 11th African Congress of Immunology

Recordings of the 11th African Congress of Immunology

FAIS 2021 – The 11th FAIS African Congress of Immunology – was held from 1st-5th August 2021. Due to the COVID-19 pandemic it was held virtually. We assembled a fantastic line-up of plenary and symposium speakers from across the globe. Plus abstracts from scientists across Africa, it was a truly memorable congress.


Sunday, August 1, 2021 – COVID-19 Symposium

Welcome address: Henry Mwandumba

17.45 min – Ifedayo Adetifa – SARS-CoV-2 seroprevalence in Africa
54.49 min – Jason Kindrachuk – Immunopathogenesis of COVID-19
1.27.30 min – Paul Moss – Cellular immunity against SARS-CoV-2
1.59.22 min – Penny Moore – Natural and vaccine-induced immunity against emerging variants

2.25.50 min – Round Table Discussion: Dr. Kondwani Jambo (moderator)


Monday, August 2, 2021 – Keynote and Plenaries

Introduction and Chair – Clive Gray

Keynote address – Siamon Gordon – Mononuclear Phagocytes in health and COVID-19 infection

New Frontiers in Immunology
Chair: Lucy Ochola
42.52 min – Federica Sallusto – Clonal analysis of the T and B cell responses to SARS-CoV-2

Monday, August 2, 2021 – Track 1: HIV Pathogenesis

Chair: Eunice Nduati

Zaza Ndhlovu – Lessons from Acute HIV infection that inform HIV cure strategies

31.38 min – Rebecca Chukwuanukwu – Evaluation of some Immune Parameters in Diabetic HIV Positive Subjects in South-East Nigeria
45.09 min – Cheusisime Kajanga – HIV-infected individuals with Cryptococcal meningitis have impaired monocyte and neutrophil phagocytic function
58.22 min – Magalli Magnoumba – Unbiased Profiling Reveals Compartmentalization of Unconventional T-Cells Within the Intestinal Mucosa Irrespective of HIV Infection

Monday, August 2, 2021 – Track 2: Cancer Epidemiology & Immunotherapy

Chair: Salem Chouaib

Asma Gati – Obesity and Breast Cancer: The multifactorial role of leptin

29.13 min – Joanina Gicobi – Metabolic fitness of resilient CD8+ T cells with high cytolytic capacity in human peripheral blood.
42.43 min – Niang Doudou Georges Massar – Involvement of IL-17A and Galectin-3 levels in breast cancer metastasis: cases of Senegalese patients

Monday, August 2, 2021 – BioStruct Symposium

Michel Modje – Introduction to structural biology

27.00 min – Emmanuel Nji – A structural biology approach to win the fight against infectious diseases

Monday, August 2, 2021 – New ways to examine immune systems

Chair: Tomabu Adjobimey

Luke O’Neill – Adventures in Inflammation Research
36.30 min – Joanna Groom – Targeting T cell interactions for tailored immunity
1.6.50 min – Mark Davis – Adventures in Human Immunology

Monday, August 2, 2021 – Track 1: Molecular/Systems Immunology

Chair: Arinola Ganiyu

Tom Scriba – T cell response determinants of tuberculosis disease progression

35.25 min – Mohammed El-Hadi Seninet – MicroRNA Profil expression in Primary biliary Cirrhosis
50.44 min – Gatien Lokossou – Low serum-derived Syncytin-2 levels in exosome at early pregnancy is a predictor of preeclampsia: a prospective pilot study in Benin, West Africa

Monday, August 2, 2021 – Track 2: Human Immunology & COVID-19

Chair: Samira Fafi-Kremer

Dorothy Yeboah-Manu – Bacterial Colonisation of the Gut

44.31 min – Agness Ethel Lakudzala – Decline in antibodies to SARS-CoV-2 over 6 months among Health Care Workers in Blantyre, Malawi
54.26 min – Marah G Chibwana – Rapid decline of SARSCoV-2 neutralising IgG antibodies in convalescent sera from Malawian adults following natural infection
1.06.35 min – Roanne S. Keeton – Studying durability of immune responses to sars-cov-2 in a cohort of healthcare workers after mild COVID-19
1.19.42 min – Thandeka Nkosi – Evaluation of SARS-CoV-2 specific T cell responses in HIV infected and uninfected individuals in KwaZulu-Natal province of South Africa.


Tuesday, August 3, 2021 – Malaria, bacteria and HIV and host immunity

Chair: Dorothy Yeboah-Manu

Phil Hansbro – Understanding pathogenesis to develop new treatments for COVID-19
31.00 min – Gordon Awandare – Investigating malaria parasite biology and immune responses in areas with varying P. falciparum transmission intensities
1.3.46 min – Erica Andersen-Nissen – Innate Immune Signatures of HIV Vaccine Immunogenicity.

Tuesday, August 3, 2021 – Track 1: Malaria

Chair: Priscilla Ngotho

Yaw Bediako – Systems based investigation of correlates of anti-malarial immunity

44.37 min – Benjamin Amoani – Effect of hookworm infection and anthelmintic treatment on naturally acquired antibody responses against the GMZ2 malaria vaccine candidate and constituent antigens
60 min – Rowland Osii – Dendritic Cell Interactions with Malaria Parasites

Tuesday, August 3, 2021 – Track 2: HIV

Chair: Gatien Lokossou

Karin Lore – Understanding the Fate of mRNA Vaccines in vivo and Mechanisms of Early Responses

32.34 min – Bongiwe Mahlobo – Novel Surface Biomarkers, Location, And Function Of T Follicular Regulatory Cells In HIV-1 Clade C Infected Lymph Nodes
43.14 min – Bahiah Meyer – A GIFT (Genital Inflammation Test) for identifying women with asymptomatic sexually transmitted infections and bacterial vaginosis who are at risk of HIV acquisition
1.1.08 min – Namani Ngema – Characterization of cytotoxic lymphocytes in the lymph nodes during treated and untreated HIV-1 clade C infection.
1.15.26 min – Andrew Ekii Obuku – HIV specific cellular attrition in HIV and S. mansoni coinfected Ugandans

Tuesday, August 3, 2021 – Tuberculosis & HIV and host immunity

Chair: Kondwani Jambo

JoAnne Flynn – The path to sterilizing immunity against tuberculosis
30.20 min – David Russell – Mycobacterium tuberculosis: Functional heterogeneity of host and pathogen in vivo
1.03.14 min  – Mike Betts – CD8+ T cell residency and recirculation in humans, relating to HIV, other viruses, and autoimmunity

Tuesday, August 3, 2021 – Track 1: TB infection, Disease & Immunity

Chair: Fouad Seghrouchni

Patricia Darrah –  Understanding Protection after IV BCG Immunization in NHP

34.50 min – David T Mzinza – Infecting strain specificity influences human alveolar macrophage mediated ex vivo control of Mycobacterium tuberculosis infection
48.54 min – Paul Ogongo –  IL-17 responses in people with latent TB is biased towards M. tuberculosis antigens with variable T-cell epitopes

Tuesday, August 3, 2021 – Track 2: Allergy, Autoimmunity & Autoinflammation

Chair: Asma GATI

Ridha Barbouche – The STAT3 pathway: exploring the frontiers between infection and allergy

35.50 min – Sabelo Hadebe – In allergic asthma, B cell IgM isotype regulates airway smooth muscle contraction at a single cell level
45.01 min – Manel Amri – Interleukin 17 stimulates mononuclear cells to kill Echinococcus granulosus by NO-dependent mechanism: immuomodulation by laminated layer
54.36 min – Sylvia Riedel – The intestinal immune system and the development of metabolic disease


Wednesday, August 4, 2021 – Innate and Adaptive immune systems

Chair: Abdallah Badou

Eric Vivier – Harnessing Innate Immunity
35.21 min – Andreas Radbruch – Immunity and immunological memory
1.04.29 min – Michal Schwartz – Harnessing bone-marrow derived macrophages to combat Alzheimer’s disease by modestly unleashing the systemic immune system by immune checkpoint blockade approach

Wednesday, August 4, 2021 – Track 1: Translational & Host Immunity

Chair: Janelisa Musaya

Reto Guler – Targeting non-coding RNAs as host-directed drug therapy for tuberculosis

35.21 min – Moustapha Babo – Immune status to rubella and toxoplasmosis of pregnant women in Dakar, Senegal.
46.32 min – Aaron P Chirambo – Immune cell cluster dynamics in the lungs of mice during Influenza A virus infection

Wednesday, August 4, 2021 – Track 2: HIV/TB/Malaria Immunopathogenesis

Chair: Jayne Sutherland

Kondwani Jambo – The impact of HIV infection on the human airway

29.25 min – Pia Steigler – T cell Responses to Mycobacterium indicus pranii Immunotherapy and adjunctive Glucocorticoid Therapy in Tuberculous Pericarditis
44.02 min – Thokozile Ngulube – A novel sub-population of neutrophils associated with cerebral malaria in children: prospective case-control study
54.24 min – Anneth-Mwasi Tumbo – HIV-1 positive and negative Tanzanian adults immunized with PfSPZ vaccine mount antibodies to circumsporozoite protein and merozoite surface protein 5

Wednesday, August 4, 2021 – FAIS General Assembly and Elections

FAIS General Assembly and Elections


Wednesday, August 4, 2021 – Society of Leukocyte Biology sponsored session
on Modulating Host Immunity

Chairs: Luis Montaner and Dominico Mavilio

Alex Shalek – Identifying And Rationally Modulating Cellular Drivers Of Enhanced and Diminished Immunity
32.25 min – Ann Ager – Overcoming T-cell homing challenges in cellular therapies for solid cancers
1.03.26 min – Lars Hviid – Antibody-mediated immunity to malaria – both ends matter!
1.33.25 min – Marina Caskey – Broadly Neutralizing Antibodies for HIV Prevention, Therapy and Cure
2.08.04 min – Ann Richmond – Modulating Host Immunity in Breast Cancer: Our Search for New Therapeutic Strategies


Thursday, August 5, 2021 – Fungal and Helminth Immunology Vignettes

Chairs: Jude Uzonna and Nada Abdel Aziz

Elia Tait Wojno – Prostaglandin regulation of type 2 inflammation
32.10 min – Bill Horsnell – Helminth regulation of immune pathology to STI’s
59.12 min – Claire Hoving – Host Recognition and Clearance of Pneumocystis
1.11.09 min  – Maria Yazdanbakhsh – Helminth infections and immune modulation:
lessons from the field and from controlled human infection studies

1.34.58 min – Roundtable

Thursday, August 5, 2021 – Guest speaker: Tomabu Adjobimey

Guest speaker: Tomabu Adjobimey – Impact of immune responses against parasites on the physiopathology of COVID-19


Thursday, August 5, 2021 – Closing Plenaries

Chair: Clive Gray

Bruce Walker – HIV and COVID-19: Learning from Patients
43.53 min – Akiko Iwasaki – Immune responses to SARS-CoV-2

1.20.57 min – Closing Address – Pa Tamba Ngom