The importance of size in cell-cell immune recognition

Prof Anton van der Merwe
Professor of Molecular Immunology, University of Oxford.

Anton van der Merwe is a Professor of Molecular Immunology at the University of Oxford. He is best known for his discovery, with Simon Davis, of the kinetic-segregation mechanism of T cell receptor (TCR) triggering, which is exploited by many other immunoreceptors. Other major discoveries include the importance of size-matching between the receptor/ligand complexes mediating immune recognition. These discoveries have influenced the development of novel therapies (e.g. bispecific reagents and CAR T cells) that exploit immune recognition. Omer Dushek and he have cofounded a company, MatchBio, to commercialise these discoveries.

SAIS – South African Immunology Society
📆 30 April 2026
🕓 16:00 – 17:00 SAST
📍 Online (Zoom)
Register:🔗 https://uct-za.zoom.us/meeting/register/4OSY_OZ7T12hO56U6iTJnA#/registration