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July 22, 2021 | Global Immunotalks Highlight: Immune responses after dengue virus infection: friend or foe? | Immunopaedia.org.za

Global Immunotalks Highlight: Immune responses after dengue virus infection: friend or foe?

Immunology research update from Immunopaedia.org.za In today’s breaking news article, we highlight Global ImmunoTalks webinar featuring Dr Tineke Cantaert  (Institut Pasteur du Cambodia & HHMI/Wellcome International Research Scholar). She began her talk highlighting the Institut Pasteur network and the main focus of her research lab: Investigation of adaptive immune responses to RNA viruses (Arboviruses: Dengue, Chikungunya Virus; Rabies virus) with a specific focus on single cells analysis platform. She then gave an overview of immune responses to Dengue virus. Dengue virus…

July 19, 2021 | What does HLA-DR expression on CD4 T cells indicate? | Immunopaedia.org.za

What does HLA-DR expression on CD4 T cells indicate?

Immunology research update from Immunopaedia.org.za. HLA-DR is a molecule typically expressed by antigen-presenting cells and is associated with antigen presentation. Interestingly HLA-DR is also expressed on T cells and has been associated with T cell activation. However, why and how activated T cells express HLA-DR is not fully understood. A recent study by Tippalagama et al. aimed to characterize the phenotype of effector CD4 T cells in active Tuberculosis. Transcriptomic profiling of non-naïve CD4 T cells from M.tb uninfected, M.tb infected and individuals with active…

July 14, 2021 | IUIS-Immunopaedia-Frontiers Webinar: Immunopathology of COVID 19 lessons from pregnancy and from ageing | Immunopaedia.org.za

IUIS-Immunopaedia-Frontiers Webinar: Immunopathology of COVID 19 lessons from pregnancy and from ageing

Immunology research update from Immunopaedia.org.za. Today’s IUIS-Immunopaedia-Frontiers Webinar highlight is on a talk by Professor Andrea Cossarizza (Director of the School of Specialization in Clinical Pathology and Clinical Biochemistry and Vice Dean of the School of Medicine at the University of Modena and Reggio Emilia). Prof Cossarizza webinar focused on “Immunopathology of COVID-19 lessons from pregnancy and ageing.” Professor Cossarizza began his talk by highlighting the major role inflammation (and hyper inflammation) play in COVID-19 pathogenesis. He also briefly described inflammatory…

July 13, 2021 | Could infection with other viruses provide protection from SARS-CoV-2? | Immunopaedia.org.za

Could infection with other viruses provide protection from SARS-CoV-2?

Immunology research update from Immunopaedia.org.za. SARS-CoV-2 replicates in the upper respiratory tract and transmission usually occurs in the first week. A strong innate immune response at this stage could reduce transmission and COVID-19 disease progression. Cheemarla et al. studied the role of the innate immune response in “restricting early SARS-CoV-2 infection using transcriptomics and biomarker-based tracking in serial patient nasopharyngeal samples and experiments with airway epithelial organoids”. The researchers found that SARS-CoV-2 replicates exponentially with a “doubling time of ∼6 h”. Interferon-stimulated genes (ISGs)…

July 8, 2021 | 10th IDA Symposium | Virtual

10th IDA Symposium

INFECTIOUS DISEASES IN AFRICA 10TH SYMPOSIUM HIV, Malaria and TB Vaccine Research in the time of the COVID-19 pandemic The 10th IDA symposia – 11-14 October 2021 (virtual) The IDA symposium aims to create knowledge and scientific literacy in Africa by enhancing the knowledge base and skills of basic and clinical immunology research being performed by students and early-career African scientists. We are now opening up the Virtual IDA Symposium to early-career scientists from across the world. The IDA has the…

July 8, 2021 | Webinar: HIV prevention: antibodies and vaccine development | Virtual

Webinar: HIV prevention: antibodies and vaccine development

HIV prevention: antibodies and vaccine development Despite 40 years of research the HIV epidemic remains a significant global health challenge and an HIV vaccine is still elusive. The recent results from the AMP trial have shown that a broadly neutralizing antibody can provide protection from infection. This has important implications for the pipeline of HIV broadly neutralizing antibodies being developed for prevention as well as vaccines that aim to elicit protective antibodies. This webinar will discuss the role of antibodies…

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